[ Started: 2025-03-25 01:04:58 CET ] [ liana v0.1.14 for BioC-3.21 from https://github.com/saezlab/liana@master (6cab46c 2024-08-07 08:58:01) ] * checking for file ‘./DESCRIPTION’ ... OK * preparing ‘liana’: * checking DESCRIPTION meta-information ... OK * installing the package to build vignettes * creating vignettes ... ERROR --- re-building ‘liana_cc2tensor.Rmd’ using rmarkdown Warning in png(..., res = dpi, units = "in") : unable to open connection to X11 display '' [2025-03-25 01:05:38] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:05:38] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:38] [INFO] [OmnipathR] Initialized cache: `/home/omnipath/.cache/OmnipathR`. [2025-03-25 01:05:38] [INFO] [OmnipathR] Package `OmnipathR` packaged: 2025-03-25 00:04:33 UTC; omnipath [2025-03-25 01:05:38] [INFO] [OmnipathR] Package `OmnipathR` date/publication: NA [2025-03-25 01:05:38] [INFO] [OmnipathR] Package `OmnipathR` built: R 4.5.0; ; 2025-03-25 00:04:34 UTC; unix [2025-03-25 01:05:38] [INFO] [OmnipathR] Package `OmnipathR` version: 3.15.9 [2025-03-25 01:05:38] [INFO] [OmnipathR] Package `OmnipathR` repository: NA [2025-03-25 01:05:38] [INFO] [OmnipathR] Session info: [version=R Under development (unstable) (2025-02-12 r87715); os=Ubuntu 24.04 LTS; system=x86_64, linux-gnu; ui=X11; language=en_GB; collate=C; ctype=en_GB.UTF-8; tz=Europe/Berlin; date=2025-03-25; pandoc=3.1.3 @ /usr/bin/ (via rmarkdown); quarto=NA] [2025-03-25 01:05:38] [INFO] [OmnipathR] External libraries: [cairo=1.18.0; cairoFT=2.13.2/2.15.0; pango=; png=1.6.43; jpeg=8.0; tiff=LIBTIFF, Version 4.5.1; tcl=8.6.14; curl=8.5.0; zlib=1.3; bzlib=1.0.8, 13-Jul-2019; xz=5.4.5; deflate=1.19; PCRE=10.42 2022-12-11; ICU=74.2; TRE=TRE 0.8.0 R_fixes (BSD); iconv=glibc 2.39; readline=8.2; BLAS=/opt/R-devel/lib/R/lib/libRblas.so; lapack=/usr/lib/x86_64-linux-gnu/lapack/liblapack.so.3.12.0; lapack_version=3.12.0] [2025-03-25 01:05:38] [INFO] [OmnipathR] CURL: version: 8.5.0; headers: 8.5.0; ssl_version: OpenSSL/3.0.13; libz_version: 1.3; libssh_version: libssh/0.10.6/openssl/zlib; libidn_version: 2.3.7; host: x86_64-pc-linux-gnu; protocols: dict, file, ftp, ftps, gopher, gophers, http, https, imap, imaps, ldap, ldaps, mqtt, pop3, pop3s, rtmp, rtmpe, rtmps, rtmpt, rtmpte, rtmpts, rtsp, scp, sftp, smb, smbs, smtp, smtps, telnet, tftp; ipv6: TRUE; http2: TRUE; idn: TRUE; url_parser: TRUE [2025-03-25 01:05:38] [TRACE] [OmnipathR] Running on a build server, wiping cache. [2025-03-25 01:05:38] [TRACE] [OmnipathR] Cache is at `/home/omnipath/.cache/OmnipathR`. [2025-03-25 01:05:38] [TRACE] [OmnipathR] Contains 1 files. [2025-03-25 01:05:38] [TRACE] [OmnipathR] Cache is locked: FALSE. [2025-03-25 01:05:38] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:05:38] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:38] [SUCCESS] [OmnipathR] Removing all cache contents from `/home/omnipath/.cache/OmnipathR`. [2025-03-25 01:05:38] [TRACE] [OmnipathR] Pandoc version: `3.1.3`. [2025-03-25 01:05:38] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/local/R/4.5-3.21/OmnipathR/db/db_def.json` (encoding: UTF-8). [2025-03-25 01:05:38] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:38] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/local/R/4.5-3.21/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8). [2025-03-25 01:05:38] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:38] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/local/R/4.5-3.21/OmnipathR/internal/urls.json` (encoding: UTF-8). [2025-03-25 01:05:38] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:38] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/local/R/4.5-3.21/OmnipathR/internal/id_types.json` (encoding: UTF-8). [2025-03-25 01:05:38] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:38] [TRACE] [OmnipathR] Cache locked: FALSE Warning: ImageMagick was built without librsvg which causes poor qualty of SVG rendering. For better results use image_read_svg() which uses the rsvg package. Quitting from liana_cc2tensor.Rmd:122-137 [unnamed-chunk-4] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Error: ! R: unbalanced graphic context push-pop `graphic-context' @ error/draw.c/RenderMVGContent/3274 --- Backtrace: ▆ 1. ├─tools::buildVignettes(dir = ".", tangle = TRUE) 2. │ ├─base::tryCatch(...) 3. │ │ └─base (local) tryCatchList(expr, classes, parentenv, handlers) 4. │ │ └─base (local) tryCatchOne(expr, names, parentenv, handlers[[1L]]) 5. │ │ └─base (local) doTryCatch(return(expr), name, parentenv, handler) 6. │ └─engine$weave(file, quiet = quiet, encoding = enc) 7. │ └─knitr:::vweave_rmarkdown(...) 8. │ └─rmarkdown::render(...) 9. │ └─knitr::knit(knit_input, knit_output, envir = envir, quiet = quiet) 10. │ └─knitr:::process_file(text, output) 11. │ ├─xfun:::handle_error(...) 12. │ ├─base::withCallingHandlers(...) 13. │ └─knitr:::process_group(group) 14. │ └─knitr:::call_block(x) 15. │ └─knitr:::block_exec(params) 16. │ └─knitr:::eng_r(options) 17. │ └─knitr:::run_hooks(before = FALSE, options, env) 18. │ └─base::do.call(hook, args, envir = envir) 19. └─knitr (local) ``(...) 20. ├─knitr:::in_base_dir(for (f in get_plot_files()) plot_crop(f)) 21. │ └─knitr:::in_dir(d, expr) 22. └─knitr::plot_crop(f) 23. └─magick::image_write(magick::image_trim(img), x) 24. └─magick:::magick_image_write(...) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Error: processing vignette 'liana_cc2tensor.Rmd' failed with diagnostics: R: unbalanced graphic context push-pop `graphic-context' @ error/draw.c/RenderMVGContent/3274 --- failed re-building ‘liana_cc2tensor.Rmd’ --- re-building ‘liana_custom_op.Rmd’ using rmarkdown [2025-03-25 01:05:57] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-03-25 01:05:57] [TRACE] [OmnipathR] Arguments for OmniPath query: [resources=[Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020],query_type=interactions] [2025-03-25 01:05:57] [INFO] [OmnipathR] Loading database `Ensembl and OMA organism names`. [2025-03-25 01:05:57] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:05:57] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:57] [INFO] [OmnipathR] Looking up in cache `https://www.ensembl.org/info/about/species.html`: key=7332486db7400730697234bad76ca0c8e4d00799, no version available. [2025-03-25 01:05:57] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:05:57] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:57] [INFO] [OmnipathR] Created new version for cache record 7332486db7400730697234bad76ca0c8e4d00799: version 1. [2025-03-25 01:05:57] [TRACE] [OmnipathR] Cache file path: /home/omnipath/.cache/OmnipathR/7332486db7400730697234bad76ca0c8e4d00799-1.html [2025-03-25 01:05:57] [INFO] [OmnipathR] Retrieving URL: `https://www.ensembl.org/info/about/species.html` [2025-03-25 01:05:57] [TRACE] [OmnipathR] Downloading by `httr2` in `download_base`. [2025-03-25 01:05:57] [TRACE] [OmnipathR] Attempt 1/3: `https://www.ensembl.org/info/about/species.html` [2025-03-25 01:05:57] [TRACE] [OmnipathR] Preparing httr2 request. [2025-03-25 01:05:57] [TRACE] [OmnipathR] The following curl options are not available: tcp_keepcnt [2025-03-25 01:05:57] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE] [2025-03-25 01:05:57] [TRACE] [OmnipathR] Sending HTTP request. [2025-03-25 01:05:57] [TRACE] [OmnipathR] HTTP 200 [2025-03-25 01:05:57] [TRACE] [OmnipathR] Downloaded 31 Kb in 0.243841s from www.ensembl.org (127 Kb/s); Redirect: 0s, DNS look up: 0.016291s, Connection: 0.035477s, Pretransfer: 0.092991s, First byte at: 0.221774s [2025-03-25 01:05:58] [INFO] [OmnipathR] Download ready [key=7332486db7400730697234bad76ca0c8e4d00799, version=1] [2025-03-25 01:05:58] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:05:58] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:58] [INFO] [OmnipathR] Cache item `7332486db7400730697234bad76ca0c8e4d00799` version 1: status changed from `unknown` to `ready`. [2025-03-25 01:05:58] [TRACE] [OmnipathR] Downloading by `generic_downloader`. [2025-03-25 01:05:58] [TRACE] [OmnipathR] Looking up in cache: `https://omabrowser.org/All/oma-species.txt`. [2025-03-25 01:05:58] [INFO] [OmnipathR] Cache record does not exist: `https://omabrowser.org/All/oma-species.txt` [2025-03-25 01:05:58] [TRACE] [OmnipathR] Could not find in cache, initiating download: `https://omabrowser.org/All/oma-species.txt`. [2025-03-25 01:05:58] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:05:58] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:58] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:05:58] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:58] [INFO] [OmnipathR] Cache item `30e690cbb55dfc63b5903ab337f34ffc2f4be397` version 1: status changed from `unknown` to `started`. [2025-03-25 01:05:58] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`. [2025-03-25 01:05:58] [INFO] [OmnipathR] Retrieving URL: `https://omabrowser.org/All/oma-species.txt` [2025-03-25 01:05:58] [TRACE] [OmnipathR] Attempt 1/3: `https://omabrowser.org/All/oma-species.txt` [2025-03-25 01:05:58] [TRACE] [OmnipathR] The following curl options are not available: tcp_keepcnt [2025-03-25 01:05:58] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE] [2025-03-25 01:05:58] [TRACE] [OmnipathR] Downloaded 130.3 Kb in 0.132289s from omabrowser.org (984.8 Kb/s); Redirect: 0s, DNS look up: 0.001158s, Connection: 0.013194s, Pretransfer: 0.047976s, First byte at: 0.062359s [2025-03-25 01:05:59] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`. [2025-03-25 01:05:59] [INFO] [OmnipathR] Download ready [key=30e690cbb55dfc63b5903ab337f34ffc2f4be397, version=1] [2025-03-25 01:05:59] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:05:59] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:59] [INFO] [OmnipathR] Cache item `30e690cbb55dfc63b5903ab337f34ffc2f4be397` version 1: status changed from `started` to `ready`. [2025-03-25 01:05:59] [INFO] [OmnipathR] Loaded database `Ensembl and OMA organism names`. [2025-03-25 01:05:59] [TRACE] [OmnipathR] Organism(s): 9606 [2025-03-25 01:05:59] [TRACE] [OmnipathR] Orthology targets: [2025-03-25 01:05:59] [TRACE] [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8). [2025-03-25 01:05:59] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:05:59] [TRACE] [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:05:59] [INFO] [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:05:59] [TRACE] [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:05:59] [INFO] [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:05:59] [TRACE] [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:05:59] [INFO] [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:05:59] [TRACE] [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:05:59] [TRACE] [OmnipathR] The following curl options are not available: tcp_keepcnt [2025-03-25 01:05:59] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE] [2025-03-25 01:06:00] [TRACE] [OmnipathR] Downloaded 236.8 Kb in 0.162032s from omnipathdb.org (1.4 Mb/s); Redirect: 0s, DNS look up: 0.001017s, Connection: 0.02177s, Pretransfer: 0.057148s, First byte at: 0.098969s [2025-03-25 01:06:00] [INFO] [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Guide2Pharma,HPMR,ICELLNET,Kirouac2010,CellTalkDB,connectomeDB2020&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:06:00] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:00] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:00] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:00] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:00] [INFO] [OmnipathR] Cache item `69503cb1a01671e7c77c0e80e6ca0ce4110a89fe` version 1: status changed from `unknown` to `started`. [2025-03-25 01:06:00] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/69503cb1a01671e7c77c0e80e6ca0ce4110a89fe-1.rds`. [2025-03-25 01:06:00] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/69503cb1a01671e7c77c0e80e6ca0ce4110a89fe-1.rds`. [2025-03-25 01:06:00] [INFO] [OmnipathR] Download ready [key=69503cb1a01671e7c77c0e80e6ca0ce4110a89fe, version=1] [2025-03-25 01:06:00] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:00] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:00] [INFO] [OmnipathR] Cache item `69503cb1a01671e7c77c0e80e6ca0ce4110a89fe` version 1: status changed from `started` to `ready`. [2025-03-25 01:06:00] [SUCCESS] [OmnipathR] Downloaded 4568 interactions. [2025-03-25 01:06:00] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-03-25 01:06:00] [TRACE] [OmnipathR] Arguments for OmniPath query: [resources=CellPhoneDB,fields=extra_attrs,query_type=interactions] [2025-03-25 01:06:00] [TRACE] [OmnipathR] Organism(s): 9606 [2025-03-25 01:06:00] [TRACE] [OmnipathR] Orthology targets: [2025-03-25 01:06:00] [TRACE] [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8). [2025-03-25 01:06:00] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:01] [TRACE] [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:01] [INFO] [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:01] [TRACE] [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:01] [INFO] [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:01] [TRACE] [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:01] [INFO] [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:01] [TRACE] [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:01] [TRACE] [OmnipathR] The following curl options are not available: tcp_keepcnt [2025-03-25 01:06:01] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE] [2025-03-25 01:06:01] [TRACE] [OmnipathR] Downloaded 128.2 Kb in 0.147941s from omnipathdb.org (866.4 Kb/s); Redirect: 0s, DNS look up: 0.00097s, Connection: 0.021159s, Pretransfer: 0.056436s, First byte at: 0.097161s [2025-03-25 01:06:01] [INFO] [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellPhoneDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:01] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:01] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:01] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:01] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:01] [INFO] [OmnipathR] Cache item `ec8c89037e2c920468342c7c2326c74a5474eedc` version 1: status changed from `unknown` to `started`. [2025-03-25 01:06:01] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/ec8c89037e2c920468342c7c2326c74a5474eedc-1.rds`. [2025-03-25 01:06:01] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/ec8c89037e2c920468342c7c2326c74a5474eedc-1.rds`. [2025-03-25 01:06:01] [INFO] [OmnipathR] Download ready [key=ec8c89037e2c920468342c7c2326c74a5474eedc, version=1] [2025-03-25 01:06:01] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:01] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:01] [INFO] [OmnipathR] Cache item `ec8c89037e2c920468342c7c2326c74a5474eedc` version 1: status changed from `started` to `ready`. [2025-03-25 01:06:01] [TRACE] [OmnipathR] Converting JSON column `extra_attrs` to list. [2025-03-25 01:06:02] [SUCCESS] [OmnipathR] Downloaded 2879 interactions. [2025-03-25 01:06:02] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-03-25 01:06:02] [TRACE] [OmnipathR] Arguments for OmniPath query: [resources=Cellinker,fields=extra_attrs,query_type=interactions] [2025-03-25 01:06:02] [TRACE] [OmnipathR] Organism(s): 9606 [2025-03-25 01:06:02] [TRACE] [OmnipathR] Orthology targets: [2025-03-25 01:06:02] [TRACE] [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8). [2025-03-25 01:06:02] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:02] [TRACE] [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:02] [INFO] [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:02] [TRACE] [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:02] [INFO] [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:02] [TRACE] [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:02] [INFO] [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:02] [TRACE] [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:02] [TRACE] [OmnipathR] The following curl options are not available: tcp_keepcnt [2025-03-25 01:06:02] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE] [2025-03-25 01:06:02] [TRACE] [OmnipathR] Downloaded 224.3 Kb in 0.158379s from omnipathdb.org (1.4 Mb/s); Redirect: 0s, DNS look up: 0.001015s, Connection: 0.019687s, Pretransfer: 0.054831s, First byte at: 0.093131s [2025-03-25 01:06:03] [INFO] [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=Cellinker&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:03] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:03] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:03] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:03] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:03] [INFO] [OmnipathR] Cache item `8173bc9dfc09711dc80f48d9c3c5bd57af3d8be5` version 1: status changed from `unknown` to `started`. [2025-03-25 01:06:03] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/8173bc9dfc09711dc80f48d9c3c5bd57af3d8be5-1.rds`. [2025-03-25 01:06:03] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/8173bc9dfc09711dc80f48d9c3c5bd57af3d8be5-1.rds`. [2025-03-25 01:06:03] [INFO] [OmnipathR] Download ready [key=8173bc9dfc09711dc80f48d9c3c5bd57af3d8be5, version=1] [2025-03-25 01:06:03] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:03] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:03] [INFO] [OmnipathR] Cache item `8173bc9dfc09711dc80f48d9c3c5bd57af3d8be5` version 1: status changed from `started` to `ready`. [2025-03-25 01:06:03] [TRACE] [OmnipathR] Converting JSON column `extra_attrs` to list. [2025-03-25 01:06:03] [SUCCESS] [OmnipathR] Downloaded 3765 interactions. [2025-03-25 01:06:03] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-03-25 01:06:03] [TRACE] [OmnipathR] Arguments for OmniPath query: [resources=talklr,fields=extra_attrs,query_type=interactions] [2025-03-25 01:06:03] [TRACE] [OmnipathR] Organism(s): 9606 [2025-03-25 01:06:03] [TRACE] [OmnipathR] Orthology targets: [2025-03-25 01:06:03] [TRACE] [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8). [2025-03-25 01:06:03] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:03] [TRACE] [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:03] [INFO] [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:03] [TRACE] [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:03] [INFO] [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:03] [TRACE] [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:03] [INFO] [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:03] [TRACE] [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:03] [TRACE] [OmnipathR] The following curl options are not available: tcp_keepcnt [2025-03-25 01:06:03] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE] [2025-03-25 01:06:03] [TRACE] [OmnipathR] Downloaded 207 Kb in 0.187394s from omnipathdb.org (1.1 Mb/s); Redirect: 0s, DNS look up: 0.000984s, Connection: 0.019621s, Pretransfer: 0.070881s, First byte at: 0.129834s [2025-03-25 01:06:04] [INFO] [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=talklr&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:04] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:04] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:04] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:04] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:04] [INFO] [OmnipathR] Cache item `b2de51666493a9c70a7b375972a2557903c14763` version 1: status changed from `unknown` to `started`. [2025-03-25 01:06:04] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/b2de51666493a9c70a7b375972a2557903c14763-1.rds`. [2025-03-25 01:06:04] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/b2de51666493a9c70a7b375972a2557903c14763-1.rds`. [2025-03-25 01:06:04] [INFO] [OmnipathR] Download ready [key=b2de51666493a9c70a7b375972a2557903c14763, version=1] [2025-03-25 01:06:04] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:04] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:04] [INFO] [OmnipathR] Cache item `b2de51666493a9c70a7b375972a2557903c14763` version 1: status changed from `started` to `ready`. [2025-03-25 01:06:04] [TRACE] [OmnipathR] Converting JSON column `extra_attrs` to list. [2025-03-25 01:06:04] [SUCCESS] [OmnipathR] Downloaded 2484 interactions. [2025-03-25 01:06:05] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-03-25 01:06:05] [TRACE] [OmnipathR] Arguments for OmniPath query: [resources=CellChatDB,fields=extra_attrs,query_type=interactions] [2025-03-25 01:06:05] [TRACE] [OmnipathR] Organism(s): 9606 [2025-03-25 01:06:05] [TRACE] [OmnipathR] Orthology targets: [2025-03-25 01:06:05] [TRACE] [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8). [2025-03-25 01:06:05] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:05] [TRACE] [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:05] [INFO] [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:05] [TRACE] [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:05] [INFO] [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:05] [TRACE] [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:05] [INFO] [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:05] [TRACE] [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:05] [TRACE] [OmnipathR] The following curl options are not available: tcp_keepcnt [2025-03-25 01:06:05] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE] [2025-03-25 01:06:05] [TRACE] [OmnipathR] Downloaded 111.9 Kb in 0.174479s from omnipathdb.org (641.3 Kb/s); Redirect: 0s, DNS look up: 0.000861s, Connection: 0.022851s, Pretransfer: 0.076449s, First byte at: 0.130355s [2025-03-25 01:06:06] [INFO] [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=CellChatDB&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=extra_attrs,sources,references,curation_effort&license=academic` [2025-03-25 01:06:06] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:06] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:06] [INFO] [OmnipathR] Cache item `fedf7fd37a8e863f804aa073f2ae480ff78001e5` version 1: status changed from `unknown` to `started`. [2025-03-25 01:06:06] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/fedf7fd37a8e863f804aa073f2ae480ff78001e5-1.rds`. [2025-03-25 01:06:06] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/fedf7fd37a8e863f804aa073f2ae480ff78001e5-1.rds`. [2025-03-25 01:06:06] [INFO] [OmnipathR] Download ready [key=fedf7fd37a8e863f804aa073f2ae480ff78001e5, version=1] [2025-03-25 01:06:06] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:06] [INFO] [OmnipathR] Cache item `fedf7fd37a8e863f804aa073f2ae480ff78001e5` version 1: status changed from `started` to `ready`. [2025-03-25 01:06:06] [TRACE] [OmnipathR] Converting JSON column `extra_attrs` to list. [2025-03-25 01:06:06] [SUCCESS] [OmnipathR] Downloaded 1894 interactions. [2025-03-25 01:06:06] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-03-25 01:06:06] [TRACE] [OmnipathR] Arguments for OmniPath query: [resources=SignaLink3,query_type=interactions] [2025-03-25 01:06:06] [TRACE] [OmnipathR] Organism(s): 9606 [2025-03-25 01:06:06] [TRACE] [OmnipathR] Orthology targets: [2025-03-25 01:06:06] [TRACE] [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8). [2025-03-25 01:06:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:06] [TRACE] [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&resources=SignaLink3&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:06:06] [INFO] [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&resources=SignaLink3&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:06:06] [TRACE] [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=SignaLink3&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:06:06] [INFO] [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&resources=SignaLink3&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:06:06] [TRACE] [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&resources=SignaLink3&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:06:06] [INFO] [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&resources=SignaLink3&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:06:06] [TRACE] [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&resources=SignaLink3&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:06:06] [TRACE] [OmnipathR] The following curl options are not available: tcp_keepcnt [2025-03-25 01:06:06] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE] [2025-03-25 01:06:06] [TRACE] [OmnipathR] Downloaded 172.1 Kb in 0.136401s from omnipathdb.org (1.2 Mb/s); Redirect: 0s, DNS look up: 0.000981s, Connection: 0.01913s, Pretransfer: 0.054904s, First byte at: 0.091668s [2025-03-25 01:06:07] [INFO] [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&resources=SignaLink3&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic` [2025-03-25 01:06:07] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:07] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:07] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:07] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:07] [INFO] [OmnipathR] Cache item `95ee739b50bbfea2c48e5c86a64525084a1dab30` version 1: status changed from `unknown` to `started`. [2025-03-25 01:06:07] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/95ee739b50bbfea2c48e5c86a64525084a1dab30-1.rds`. [2025-03-25 01:06:07] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/95ee739b50bbfea2c48e5c86a64525084a1dab30-1.rds`. [2025-03-25 01:06:07] [INFO] [OmnipathR] Download ready [key=95ee739b50bbfea2c48e5c86a64525084a1dab30, version=1] [2025-03-25 01:06:07] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:07] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:07] [INFO] [OmnipathR] Cache item `95ee739b50bbfea2c48e5c86a64525084a1dab30` version 1: status changed from `started` to `ready`. [2025-03-25 01:06:07] [SUCCESS] [OmnipathR] Downloaded 1796 interactions. [2025-03-25 01:06:07] [TRACE] [OmnipathR] Processing args for OmniPath query [2025-03-25 01:06:07] [TRACE] [OmnipathR] Arguments for OmniPath query: [wide=FALSE,resources=SignaLink_function,query_type=annotations] [2025-03-25 01:06:07] [TRACE] [OmnipathR] Organism(s): 9606 [2025-03-25 01:06:07] [TRACE] [OmnipathR] Orthology targets: [2025-03-25 01:06:07] [TRACE] [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8). [2025-03-25 01:06:07] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:07] [TRACE] [OmnipathR] Looking up in cache: `https://omnipathdb.org/annotations?resources=SignaLink_function&license=academic` [2025-03-25 01:06:07] [INFO] [OmnipathR] Cache record does not exist: `https://omnipathdb.org/annotations?resources=SignaLink_function&license=academic` [2025-03-25 01:06:07] [TRACE] [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/annotations?resources=SignaLink_function&license=academic` [2025-03-25 01:06:07] [INFO] [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/annotations?resources=SignaLink_function&license=academic` [2025-03-25 01:06:07] [TRACE] [OmnipathR] Attempting `https://omnipathdb.org/annotations?resources=SignaLink_function&license=academic` [2025-03-25 01:06:07] [INFO] [OmnipathR] Retrieving URL: `https://omnipathdb.org/annotations?resources=SignaLink_function&license=academic` [2025-03-25 01:06:07] [TRACE] [OmnipathR] Attempt 1/3: `https://omnipathdb.org/annotations?resources=SignaLink_function&license=academic` [2025-03-25 01:06:07] [TRACE] [OmnipathR] The following curl options are not available: tcp_keepcnt [2025-03-25 01:06:07] [TRACE] [OmnipathR] Curl options: [connecttimeout=10,timeout=300,debugfunction=,verbose=FALSE,tcp_keepalive=TRUE,tcp_keepintvl=10,tcp_keepidle=10,upkeep_interval_ms=30000,ssl_verifypeer=TRUE,ssl_verifyhost=TRUE] [2025-03-25 01:06:07] [TRACE] [OmnipathR] Downloaded 26 Kb in 0.110512s from omnipathdb.org (235.7 Kb/s); Redirect: 0s, DNS look up: 0.001027s, Connection: 0.02274s, Pretransfer: 0.058275s, First byte at: 0.1022s [2025-03-25 01:06:08] [INFO] [OmnipathR] Successfully retrieved: `https://omnipathdb.org/annotations?resources=SignaLink_function&license=academic` [2025-03-25 01:06:08] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:08] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:08] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:08] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:08] [INFO] [OmnipathR] Cache item `4190db12b9aabca9c0851ec84aa3fbb71b5dfbcd` version 1: status changed from `unknown` to `started`. [2025-03-25 01:06:08] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/4190db12b9aabca9c0851ec84aa3fbb71b5dfbcd-1.rds`. [2025-03-25 01:06:08] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/4190db12b9aabca9c0851ec84aa3fbb71b5dfbcd-1.rds`. [2025-03-25 01:06:08] [INFO] [OmnipathR] Download ready [key=4190db12b9aabca9c0851ec84aa3fbb71b5dfbcd, version=1] [2025-03-25 01:06:08] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2025-03-25 01:06:08] [TRACE] [OmnipathR] JSON validation successful: TRUE [2025-03-25 01:06:08] [INFO] [OmnipathR] Cache item `4190db12b9aabca9c0851ec84aa3fbb71b5dfbcd` version 1: status changed from `started` to `ready`. [2025-03-25 01:06:08] [SUCCESS] [OmnipathR] Downloaded 2001 annotation records. [2025-03-25 01:06:09] [TRACE] [OmnipathR] Bypassing call: `OmnipathR::filter_intercell_network(., simplify = FALSE, ...)`. [2025-03-25 01:06:09] [TRACE] [OmnipathR] This behaviour is intended for running R CMD check within limited time and is triggered solely by the user name. Please report if you see this anywhere outside of a Bioconductor build server. Quitting from liana_custom_op.Rmd:158-196 [pm_omni] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Error in `UseMethod()`: ! no applicable method for 'tbl_vars' applied to an object of class "NULL" --- Backtrace: ▆ 1. ├─liana::generate_omni(...) 2. │ └─... %>% ... 3. └─dplyr::distinct_at(...) 4. └─dplyr:::manip_at(...) 5. └─dplyr:::tbl_at_syms(...) 6. └─dplyr:::tbl_at_vars(...) 7. └─dplyr::tbl_vars(tbl) 8. ├─dplyr:::new_sel_vars(tbl_vars_dispatch(x), group_vars(x)) 9. │ └─base::structure(...) 10. └─dplyr:::tbl_vars_dispatch(x) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Error: processing vignette 'liana_custom_op.Rmd' failed with diagnostics: no applicable method for 'tbl_vars' applied to an object of class "NULL" --- failed re-building ‘liana_custom_op.Rmd’ --- re-building ‘liana_devel.Rmd’ using rmarkdown --- finished re-building ‘liana_devel.Rmd’ --- re-building ‘liana_nichenet.Rmd’ using rmarkdown Quitting from liana_nichenet.Rmd:42-50 [unnamed-chunk-2] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Error in `library()`: ! there is no package called 'nichenetr' --- Backtrace: ▆ 1. └─base::library(nichenetr) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Error: processing vignette 'liana_nichenet.Rmd' failed with diagnostics: there is no package called 'nichenetr' --- failed re-building ‘liana_nichenet.Rmd’ --- re-building ‘liana_ortho.Rmd’ using rmarkdown [2025-03-25 01:07:21] [TRACE] [OmnipathR] Bypassing call: `homologene_raw()`. [2025-03-25 01:07:21] [TRACE] [OmnipathR] This behaviour is intended for running R CMD check within limited time and is triggered solely by the user name. Please report if you see this anywhere outside of a Bioconductor build server. Quitting from liana_ortho.Rmd:72-74 [show_taxid] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Error in `h()`: ! error in evaluating the argument 'object' in selecting a method for function 'na.omit': no applicable method for 'pull' applied to an object of class "list" --- Backtrace: ▆ 1. ├─liana::show_homologene() 2. │ └─... %>% print(n = nrow(.)) 3. ├─base::print(., n = nrow(.)) 4. ├─dplyr::arrange(., name) 5. ├─stats::na.omit(.) 6. ├─tibble::tibble(ncbi_taxid = ., name = common_name(.), latin = latin_name(.)) 7. │ └─tibble:::tibble_quos(xs, .rows, .name_repair) 8. │ └─rlang::eval_tidy(xs[[j]], mask) 9. ├─base::unique(.) 10. ├─dplyr::pull(., ncbi_taxid) 11. └─base::.handleSimpleError(...) 12. └─base (local) h(simpleError(msg, call)) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Error: processing vignette 'liana_ortho.Rmd' failed with diagnostics: error in evaluating the argument 'object' in selecting a method for function 'na.omit': no applicable method for 'pull' applied to an object of class "list" --- failed re-building ‘liana_ortho.Rmd’ --- re-building ‘liana_tutorial.Rmd’ using rmarkdown Warning: ImageMagick was built without librsvg which causes poor qualty of SVG rendering. For better results use image_read_svg() which uses the rsvg package. Quitting from liana_tutorial.Rmd:150-155 [liana_dotplot] ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Error: ! R: geometry does not contain image `/tmp/Rtmp3BSLzY/Rbuild33e6864f7ef543/liana/vignettes/liana_tutorial_files/figure-html/liana_dotplot-1.svg' @ warning/attribute.c/GetImageBoundingBox/534 --- Backtrace: ▆ 1. ├─tools::buildVignettes(dir = ".", tangle = TRUE) 2. │ ├─base::tryCatch(...) 3. │ │ └─base (local) tryCatchList(expr, classes, parentenv, handlers) 4. │ │ └─base (local) tryCatchOne(expr, names, parentenv, handlers[[1L]]) 5. │ │ └─base (local) doTryCatch(return(expr), name, parentenv, handler) 6. │ └─engine$weave(file, quiet = quiet, encoding = enc) 7. │ └─knitr:::vweave_rmarkdown(...) 8. │ └─rmarkdown::render(...) 9. │ └─knitr::knit(knit_input, knit_output, envir = envir, quiet = quiet) 10. │ └─knitr:::process_file(text, output) 11. │ ├─xfun:::handle_error(...) 12. │ ├─base::withCallingHandlers(...) 13. │ └─knitr:::process_group(group) 14. │ └─knitr:::call_block(x) 15. │ └─knitr:::block_exec(params) 16. │ └─knitr:::eng_r(options) 17. │ └─knitr:::run_hooks(before = FALSE, options, env) 18. │ └─base::do.call(hook, args, envir = envir) 19. └─knitr (local) ``(...) 20. ├─knitr:::in_base_dir(for (f in get_plot_files()) plot_crop(f)) 21. │ └─knitr:::in_dir(d, expr) 22. └─knitr::plot_crop(f) 23. ├─magick::image_write(magick::image_trim(img), x) 24. │ └─magick:::assert_image(image) 25. └─magick::image_trim(img) 26. └─magick:::magick_image_trim(image, fuzz) ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ Error: processing vignette 'liana_tutorial.Rmd' failed with diagnostics: R: geometry does not contain image `/tmp/Rtmp3BSLzY/Rbuild33e6864f7ef543/liana/vignettes/liana_tutorial_files/figure-html/liana_dotplot-1.svg' @ warning/attribute.c/GetImageBoundingBox/534 --- failed re-building ‘liana_tutorial.Rmd’ SUMMARY: processing the following files failed: ‘liana_cc2tensor.Rmd’ ‘liana_custom_op.Rmd’ ‘liana_nichenet.Rmd’ ‘liana_ortho.Rmd’ ‘liana_tutorial.Rmd’ Error: Vignette re-building failed. Execution halted [ Finished: 2025-03-25 01:08:33 CET ]