[ Started: 2023-06-15 23:04:52 CEST ]
[ OmnipathR v3.9.6 for BioC-3.17 from https://github.com/saezlab/OmnipathR@master ]

* checking for file ‘./DESCRIPTION’ ... OK
* preparing ‘OmnipathR’:
* checking DESCRIPTION meta-information ... OK
* installing the package to build vignettes
* creating vignettes ... ERROR
--- re-building ‘bioc_workshop.Rmd’ using rmarkdown
Warning in png(..., res = dpi, units = "in") :
  unable to open connection to X11 display ''
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:02] [INFO]    [OmnipathR] Initialized cache: `/home/omnipath/.cache/OmnipathR`.
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Running on a build server, wiping cache.
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Cache is at `/home/omnipath/.cache/OmnipathR`.
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Contains 1 files.
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Cache is locked: FALSE.
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:02] [SUCCESS] [OmnipathR] Removing all cache contents from `/home/omnipath/.cache/OmnipathR`.
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Pandoc version: `2.9.2.1`.
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Reading JSON from `/tmp/RtmpcyogVS/Rinst14d2b37e434fee/OmnipathR/db/db_def.json` (encoding: UTF-8).
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Reading JSON from `/tmp/RtmpcyogVS/Rinst14d2b37e434fee/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8).
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Reading JSON from `/tmp/RtmpcyogVS/Rinst14d2b37e434fee/OmnipathR/internal/urls.json` (encoding: UTF-8).
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Reading JSON from `/tmp/RtmpcyogVS/Rinst14d2b37e434fee/OmnipathR/internal/id_types.json` (encoding: UTF-8).
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Cache locked: FALSE
[2023-06-15 23:05:02] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea,tf_target,collectri&organisms=9606&dorothea_levels=A,B&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2023-06-15 23:05:02] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea,tf_target,collectri&organisms=9606&dorothea_levels=A,B&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2023-06-15 23:05:02] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=dorothea,tf_target,collectri&organisms=9606&dorothea_levels=A,B&fields=sources,references,curation_effort,dorothea_level&license=academic`
[2023-06-15 23:05:03] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:03] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:03] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:03] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:03] [INFO]    [OmnipathR] Cache item `8e1fed15bbe7704374f40d278e719e18b4a9d60f` version 1: status changed from `unknown` to `started`.
[2023-06-15 23:05:03] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/8e1fed15bbe7704374f40d278e719e18b4a9d60f-1.rds`.
[2023-06-15 23:05:03] [TRACE]   [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/8e1fed15bbe7704374f40d278e719e18b4a9d60f-1.rds`.
[2023-06-15 23:05:03] [INFO]    [OmnipathR] Download ready [key=8e1fed15bbe7704374f40d278e719e18b4a9d60f, version=1]
[2023-06-15 23:05:03] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:03] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:03] [INFO]    [OmnipathR] Cache item `8e1fed15bbe7704374f40d278e719e18b4a9d60f` version 1: status changed from `started` to `ready`.
[2023-06-15 23:05:06] [SUCCESS] [OmnipathR] Downloaded 121661 interactions.
[2023-06-15 23:05:09] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/enzsub?genesymbols=yes&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2023-06-15 23:05:09] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/enzsub?genesymbols=yes&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2023-06-15 23:05:09] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/enzsub?genesymbols=yes&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2023-06-15 23:05:10] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:10] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:10] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:10] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:10] [INFO]    [OmnipathR] Cache item `a6f560033dff45b503a8016c14c974c4c04b5967` version 1: status changed from `unknown` to `started`.
[2023-06-15 23:05:10] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/a6f560033dff45b503a8016c14c974c4c04b5967-1.rds`.
[2023-06-15 23:05:10] [TRACE]   [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/a6f560033dff45b503a8016c14c974c4c04b5967-1.rds`.
[2023-06-15 23:05:10] [INFO]    [OmnipathR] Download ready [key=a6f560033dff45b503a8016c14c974c4c04b5967, version=1]
[2023-06-15 23:05:10] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:10] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:10] [INFO]    [OmnipathR] Cache item `a6f560033dff45b503a8016c14c974c4c04b5967` version 1: status changed from `started` to `ready`.
[2023-06-15 23:05:11] [SUCCESS] [OmnipathR] Downloaded 43269 enzyme-substrate relationships.
[2023-06-15 23:05:12] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2023-06-15 23:05:12] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2023-06-15 23:05:12] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2023-06-15 23:05:13] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:13] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:13] [INFO]    [OmnipathR] Cache item `a7b21d9d80a3837a50268df16d168128fc1c6ede` version 1: status changed from `unknown` to `started`.
[2023-06-15 23:05:13] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/a7b21d9d80a3837a50268df16d168128fc1c6ede-1.rds`.
[2023-06-15 23:05:13] [TRACE]   [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/a7b21d9d80a3837a50268df16d168128fc1c6ede-1.rds`.
[2023-06-15 23:05:13] [INFO]    [OmnipathR] Download ready [key=a7b21d9d80a3837a50268df16d168128fc1c6ede, version=1]
[2023-06-15 23:05:13] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:13] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:13] [INFO]    [OmnipathR] Cache item `a7b21d9d80a3837a50268df16d168128fc1c6ede` version 1: status changed from `started` to `ready`.
[2023-06-15 23:05:16] [SUCCESS] [OmnipathR] Downloaded 81529 interactions.
[2023-06-15 23:05:16] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/complexes?license=academic`
[2023-06-15 23:05:16] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/complexes?license=academic`
[2023-06-15 23:05:16] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/complexes?license=academic`
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:17] [INFO]    [OmnipathR] Cache item `d562abda40303226daf98b436df9cb85eaeb2ef3` version 1: status changed from `unknown` to `started`.
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/d562abda40303226daf98b436df9cb85eaeb2ef3-1.rds`.
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/d562abda40303226daf98b436df9cb85eaeb2ef3-1.rds`.
[2023-06-15 23:05:17] [INFO]    [OmnipathR] Download ready [key=d562abda40303226daf98b436df9cb85eaeb2ef3, version=1]
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:17] [INFO]    [OmnipathR] Cache item `d562abda40303226daf98b436df9cb85eaeb2ef3` version 1: status changed from `started` to `ready`.
[2023-06-15 23:05:17] [SUCCESS] [OmnipathR] Downloaded 35459 protein complexes.
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:17] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/annotations?resources=UniProt_location&license=academic`
[2023-06-15 23:05:17] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/annotations?resources=UniProt_location&license=academic`
[2023-06-15 23:05:17] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/annotations?resources=UniProt_location&license=academic`
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:19] [INFO]    [OmnipathR] Cache item `f2e7cc5e753cd4e22d458171359dea86781ebae8` version 1: status changed from `unknown` to `started`.
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/f2e7cc5e753cd4e22d458171359dea86781ebae8-1.rds`.
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/f2e7cc5e753cd4e22d458171359dea86781ebae8-1.rds`.
[2023-06-15 23:05:19] [INFO]    [OmnipathR] Download ready [key=f2e7cc5e753cd4e22d458171359dea86781ebae8, version=1]
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:19] [INFO]    [OmnipathR] Cache item `f2e7cc5e753cd4e22d458171359dea86781ebae8` version 1: status changed from `started` to `ready`.
[2023-06-15 23:05:19] [SUCCESS] [OmnipathR] Downloaded 76260 annotation records.
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:19] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/annotations?resources=Uniprot_location&license=academic`
[2023-06-15 23:05:19] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/annotations?resources=Uniprot_location&license=academic`
[2023-06-15 23:05:19] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/annotations?resources=Uniprot_location&license=academic`
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:20] [INFO]    [OmnipathR] Cache item `07dc3ca232cbc620ab6be7d21a3a41bfc7b2d3e1` version 1: status changed from `unknown` to `started`.
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/07dc3ca232cbc620ab6be7d21a3a41bfc7b2d3e1-1.rds`.
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/07dc3ca232cbc620ab6be7d21a3a41bfc7b2d3e1-1.rds`.
[2023-06-15 23:05:20] [INFO]    [OmnipathR] Download ready [key=07dc3ca232cbc620ab6be7d21a3a41bfc7b2d3e1, version=1]
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:20] [INFO]    [OmnipathR] Cache item `07dc3ca232cbc620ab6be7d21a3a41bfc7b2d3e1` version 1: status changed from `started` to `ready`.
[2023-06-15 23:05:20] [SUCCESS] [OmnipathR] Downloaded 0 annotation records.
[2023-06-15 23:05:20] [FATAL]   [OmnipathR] Downloading the entire annotations database is not allowed by default because of its huge size (>1GB). If you really want to do that, you find static files at https://archive.omnipathdb.org/. However we recommend to query a set of proteins or a few resources, depending on your interest.
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] Loaded data from RDS `/home/omnipath/.cache/OmnipathR/f2e7cc5e753cd4e22d458171359dea86781ebae8-1.rds`.
[2023-06-15 23:05:20] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/annotations?resources=UniProt_location&license=academic`
[2023-06-15 23:05:20] [SUCCESS] [OmnipathR] Loaded 76260 annotation records from cache.
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:20] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/annotations?resources=HPA_tissue&proteins=DLL1,MEIS2,PHOX2A,BACH1,KLF11,FOXO3,MEFV&license=academic`
[2023-06-15 23:05:20] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/annotations?resources=HPA_tissue&proteins=DLL1,MEIS2,PHOX2A,BACH1,KLF11,FOXO3,MEFV&license=academic`
[2023-06-15 23:05:20] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/annotations?resources=HPA_tissue&proteins=DLL1,MEIS2,PHOX2A,BACH1,KLF11,FOXO3,MEFV&license=academic`
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:24] [INFO]    [OmnipathR] Cache item `92ead83eb455386da8cefb938ee16521d1b5f02d` version 1: status changed from `unknown` to `started`.
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/92ead83eb455386da8cefb938ee16521d1b5f02d-1.rds`.
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/92ead83eb455386da8cefb938ee16521d1b5f02d-1.rds`.
[2023-06-15 23:05:24] [INFO]    [OmnipathR] Download ready [key=92ead83eb455386da8cefb938ee16521d1b5f02d, version=1]
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:24] [INFO]    [OmnipathR] Cache item `92ead83eb455386da8cefb938ee16521d1b5f02d` version 1: status changed from `started` to `ready`.
[2023-06-15 23:05:24] [SUCCESS] [OmnipathR] Downloaded 3870 annotation records.
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:24] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/annotations?resources=SignaLink_pathway&license=academic`
[2023-06-15 23:05:24] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/annotations?resources=SignaLink_pathway&license=academic`
[2023-06-15 23:05:24] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/annotations?resources=SignaLink_pathway&license=academic`
[2023-06-15 23:05:25] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:25] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:25] [INFO]    [OmnipathR] Cache item `48f6d1c796292ce438ca19de4baf3e99ff368b61` version 1: status changed from `unknown` to `started`.
[2023-06-15 23:05:25] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/48f6d1c796292ce438ca19de4baf3e99ff368b61-1.rds`.
[2023-06-15 23:05:25] [TRACE]   [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/48f6d1c796292ce438ca19de4baf3e99ff368b61-1.rds`.
[2023-06-15 23:05:25] [INFO]    [OmnipathR] Download ready [key=48f6d1c796292ce438ca19de4baf3e99ff368b61, version=1]
[2023-06-15 23:05:25] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:25] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:25] [INFO]    [OmnipathR] Cache item `48f6d1c796292ce438ca19de4baf3e99ff368b61` version 1: status changed from `started` to `ready`.
[2023-06-15 23:05:25] [SUCCESS] [OmnipathR] Downloaded 2487 annotation records.
[2023-06-15 23:05:25] [TRACE]   [OmnipathR] Loaded data from RDS `/home/omnipath/.cache/OmnipathR/a7b21d9d80a3837a50268df16d168128fc1c6ede-1.rds`.
[2023-06-15 23:05:25] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2023-06-15 23:05:27] [SUCCESS] [OmnipathR] Loaded 81529 interactions from cache.
[2023-06-15 23:05:27] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2023-06-15 23:05:27] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:28] [TRACE]   [OmnipathR] Loaded data from RDS `/home/omnipath/.cache/OmnipathR/48f6d1c796292ce438ca19de4baf3e99ff368b61-1.rds`.
[2023-06-15 23:05:28] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/annotations?resources=SignaLink_pathway&license=academic`
[2023-06-15 23:05:28] [SUCCESS] [OmnipathR] Loaded 2487 annotation records from cache.
[2023-06-15 23:05:28] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/intercell?license=academic`
[2023-06-15 23:05:28] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/intercell?license=academic`
[2023-06-15 23:05:28] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/intercell?license=academic`
[2023-06-15 23:05:29] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:29] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:29] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:29] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:29] [INFO]    [OmnipathR] Cache item `88868f24833199a6a4a8e27980fa32cd50c1c600` version 1: status changed from `unknown` to `started`.
[2023-06-15 23:05:29] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/88868f24833199a6a4a8e27980fa32cd50c1c600-1.rds`.
[2023-06-15 23:05:31] [TRACE]   [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/88868f24833199a6a4a8e27980fa32cd50c1c600-1.rds`.
[2023-06-15 23:05:31] [INFO]    [OmnipathR] Download ready [key=88868f24833199a6a4a8e27980fa32cd50c1c600, version=1]
[2023-06-15 23:05:31] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:31] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:31] [INFO]    [OmnipathR] Cache item `88868f24833199a6a4a8e27980fa32cd50c1c600` version 1: status changed from `started` to `ready`.
[2023-06-15 23:05:31] [SUCCESS] [OmnipathR] Downloaded 332447 intercellular communication role records.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Bypassing call: `import_intercell_network(high_confidence = TRUE)`.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] This behaviour is intended for running R CMD check within limited time and is triggered solely by the user name. Please report if you see this anywhere outside of a Bioconductor build server.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Bypassing call: `import_intercell_network()`.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] This behaviour is intended for running R CMD check within limited time and is triggered solely by the user name. Please report if you see this anywhere outside of a Bioconductor build server.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Bypassing call: `filter_intercell_network(icn, ligand_receptor = TRUE, consensus_percentile = 30, `.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Bypassing call: `    loc_consensus_percentile = 50, simplify = TRUE)`.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] This behaviour is intended for running R CMD check within limited time and is triggered solely by the user name. Please report if you see this anywhere outside of a Bioconductor build server.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Reading JSON from `https://omnipathdb.org/resources` (encoding: UTF-8).
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:32] [INFO]    [OmnipathR] Cache record does not exist: `https://omnipathdb.org/intercell_summary`
[2023-06-15 23:05:32] [INFO]    [OmnipathR] Retrieving URL: `https://omnipathdb.org/intercell_summary`
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Attempt 1/3: `https://omnipathdb.org/intercell_summary`
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:32] [INFO]    [OmnipathR] Cache item `4609206529e6ae997a8de976fe1277b3b74cc032` version 1: status changed from `unknown` to `started`.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/4609206529e6ae997a8de976fe1277b3b74cc032-1.rds`.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/4609206529e6ae997a8de976fe1277b3b74cc032-1.rds`.
[2023-06-15 23:05:32] [INFO]    [OmnipathR] Download ready [key=4609206529e6ae997a8de976fe1277b3b74cc032, version=1]
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8).
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] JSON validation successful: TRUE
[2023-06-15 23:05:32] [INFO]    [OmnipathR] Cache item `4609206529e6ae997a8de976fe1277b3b74cc032` version 1: status changed from `started` to `ready`.
[2023-06-15 23:05:32] [SUCCESS] [OmnipathR] Downloaded 1098 records.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Bypassing call: `translate_ids(d, uniprot_id = uniprot, genesymbol)`.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] This behaviour is intended for running R CMD check within limited time and is triggered solely by the user name. Please report if you see this anywhere outside of a Bioconductor build server.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Bypassing call: `go_ontology_download()`.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] This behaviour is intended for running R CMD check within limited time and is triggered solely by the user name. Please report if you see this anywhere outside of a Bioconductor build server.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Bypassing call: `relations_table_to_graph(go$rel_tbl_c2p)`.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] This behaviour is intended for running R CMD check within limited time and is triggered solely by the user name. Please report if you see this anywhere outside of a Bioconductor build server.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] Bypassing call: `ontology_ensure_name("GO:0000022")`.
[2023-06-15 23:05:32] [TRACE]   [OmnipathR] This behaviour is intended for running R CMD check within limited time and is triggered solely by the user name. Please report if you see this anywhere outside of a Bioconductor build server.
--- finished re-building ‘bioc_workshop.Rmd’

--- re-building ‘db_manager.Rmd’ using rmarkdown
[2023-06-15 23:05:33] [INFO]    [OmnipathR] Loading database `UniProt-GeneSymbol table`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `(function (to, from = "accession", reviewed = TRUE, organism = 9606) `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `{`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    .slow_doctest()`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    From <- To <- NULL`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    strip_semicol <- function(v) {`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        sub(";$", "", v)`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    }`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    ids <- c(.nse_ensure_str(!!enquo(to)), .nse_ensure_str(!!enquo(from)))`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    reviewed <- if ("trembl" %in% ids) `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        FALSE`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    else if ("swissprot" %in% ids) `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        TRUE`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    else reviewed`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    to <- .nse_ensure_str(!!enquo(to)) %>% uniprot_id_type`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    from <- .nse_ensure_str(!!enquo(from)) %>% uniprot_id_type`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    reens <- "ENS[A-Z]+\\d+"`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    to_ens <- to == "xref_ensembl"`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    from_ens <- from == "xref_ensembl"`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    log_trace(paste0("Creating ID mapping table from `%s` to `%s`, ", `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        "for organism %d (only reviewed: %s)"), from, to, organism, `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        reviewed)`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    c(from, to) %>% all_uniprots(reviewed = reviewed, organism = organism) %>% `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        rename(From = 1, To = 2) %>% mutate(From = strip_semicol(From), `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        To = strip_semicol(To)) %>% separate_rows(From, sep = ";") %>% `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        separate_rows(To, sep = ";") %>% filter(!is.na(From) & `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        !is.na(To)) %>% {`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        if (from_ens) `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `            mutate(., From = str_extract(From, reens))`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        else .`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    } %>% {`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        if (to_ens) `.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `            mutate(., To = str_extract(To, reens))`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `        else .`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `    } %>% trim_and_distinct`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] Bypassing call: `})(to = "genesymbol", organism = 9606L)`.
[2023-06-15 23:05:33] [TRACE]   [OmnipathR] This behaviour is intended for running R CMD check within limited time and is triggered solely by the user name. Please report if you see this anywhere outside of a Bioconductor build server.
[2023-06-15 23:05:33] [INFO]    [OmnipathR] Loaded database `UniProt-GeneSymbol table`.
--- finished re-building ‘db_manager.Rmd’

--- re-building ‘drug_targets.Rmd’ using rmarkdown
[2023-06-15 23:05:44] [TRACE]   [OmnipathR] Loaded data from RDS `/home/omnipath/.cache/OmnipathR/a7b21d9d80a3837a50268df16d168128fc1c6ede-1.rds`.
[2023-06-15 23:05:44] [INFO]    [OmnipathR] Loaded from cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&license=academic`
[2023-06-15 23:05:46] [SUCCESS] [OmnipathR] Loaded 81529 interactions from cache.
Warning: ImageMagick was built without librsvg which causes poor qualty of SVG rendering.
For better results use image_read_svg() which uses the rsvg package.

 *** caught segfault ***
address (nil), cause 'memory not mapped'

Traceback:
 1: magick_image_write(image, format, quality, depth, density, comment,     compression)
 2: magick::image_write(magick::image_trim(img), x)
 3: plot_crop(f)
 4: in_dir(d, expr)
 5: in_base_dir(for (f in get_plot_files()) plot_crop(f))
 6: (function (before, options, envir) {    if (before)         return()    in_base_dir(for (f in get_plot_files()) plot_crop(f))})(before = FALSE, options = list(eval = TRUE, echo = TRUE, results = "markup",     tidy = FALSE, tidy.opts = NULL, collapse = FALSE, prompt = FALSE,     comment = "##", highlight = TRUE, size = "normalsize", background = "#F7F7F7",     strip.white = TRUE, cache = 0, cache.path = "drug_targets_cache/html/",     cache.vars = NULL, cache.lazy = TRUE, dependson = NULL, autodep = FALSE,     cache.rebuild = FALSE, fig.keep = "high", fig.show = "asis",     fig.align = "default", fig.path = "/tmp/RtmpcyogVS/Rbuild14d2b34de0667e/OmnipathR/vignettes/drug_targets_files/figure-html/",     dev = "svg", dev.args = NULL, dpi = 192, fig.ext = "svg",     fig.width = 8, fig.height = 5, fig.env = "figure", fig.cap = NULL,     fig.scap = NA, fig.lp = "fig:", fig.subcap = NULL, fig.pos = "",     out.width = "100%", out.height = NULL, out.extra = NULL,     fig.retina = 2, external = TRUE, sanitize = FALSE, interval = 1,     aniopts = "controls,loop", warning = TRUE, error = FALSE,     message = TRUE, render = NULL, ref.label = NULL, child = NULL,     engine = "R", split = FALSE, include = TRUE, purl = TRUE,     crop = TRUE, label = "unnamed-chunk-12", code = c("V(cisplatin_network)$node_type <-",     "    ifelse(", "        V(cisplatin_network)$name %in% source_nodes,",     "        \"direct drug target\",", "        ifelse(", "            V(cisplatin_network)$name %in% target_nodes,",     "            \"POI\",", "            \"intermediate node\"",     "        )", "    )", "", "ggraph(", "    cisplatin_network,",     "    layout = \"lgl\",", "    area = vcount(cisplatin_network)^2.3,",     "    repulserad = vcount(cisplatin_network)^1.2,", "    coolexp = 1.1",     ") +", "geom_edge_link(", "    aes(", "        start_cap = label_rect(node1.name),",     "        end_cap = label_rect(node2.name)),", "        arrow = arrow(length = unit(4, \"mm\")",     "    ),", "    edge_width = .5,", "    edge_alpha = .2",     ") +", "geom_node_point() +", "geom_node_label(aes(label = name, color = node_type)) +",     "scale_color_discrete(", "    guide = guide_legend(title = \"Node type\")",     ") +", "theme_bw() +", "xlab(\"\") +", "ylab(\"\") +", "ggtitle(\"Cisplatin induced network\")"    ), out.width.px = "100%", out.height.px = 480, params.src = "",     fig.alt = NULL, fig.num = 1), envir = <environment>)
 7: do.call(hook, args, envir = envir)
 8: run_hooks(before = FALSE, options, env)
 9: eng_r(options)
10: block_exec(params)
11: call_block(x)
12: process_group.block(group)
13: process_group(group)
14: withCallingHandlers(if (tangle) process_tangle(group) else process_group(group),     error = function(e) if (xfun::pkg_available("rlang", "1.0.0") &&         !xfun::check_old_package("learnr", "0.11.3")) rlang::entrace(e))
15: withCallingHandlers(withCallingHandlers(if (tangle) process_tangle(group) else process_group(group),     error = function(e) if (xfun::pkg_available("rlang", "1.0.0") &&         !xfun::check_old_package("learnr", "0.11.3")) rlang::entrace(e)),     error = function(e) {        setwd(wd)        write_utf8(res, output %n% stdout())        message("\nQuitting from lines ", paste(current_lines(i),             collapse = "-"), if (labels[i] != "")             sprintf(" [%s]", labels[i]), sprintf(" (%s)", knit_concord$get("infile")))    })
16: process_file(text, output)
17: knitr::knit(knit_input, knit_output, envir = envir, quiet = quiet)
18: rmarkdown::render(file, encoding = encoding, quiet = quiet, envir = globalenv(),     output_dir = getwd(), ...)
19: vweave_rmarkdown(...)
20: engine$weave(file, quiet = quiet, encoding = enc)
21: doTryCatch(return(expr), name, parentenv, handler)
22: tryCatchOne(expr, names, parentenv, handlers[[1L]])
23: tryCatchList(expr, classes, parentenv, handlers)
24: tryCatch({    engine$weave(file, quiet = quiet, encoding = enc)    setwd(startdir)    output <- find_vignette_product(name, by = "weave", engine = engine)    if (!have.makefile && vignette_is_tex(output)) {        texi2pdf(file = output, clean = FALSE, quiet = quiet)        output <- find_vignette_product(name, by = "texi2pdf",             engine = engine)    }    outputs <- c(outputs, output)}, error = function(e) {    thisOK <<- FALSE    fails <<- c(fails, file)    message(gettextf("Error: processing vignette '%s' failed with diagnostics:\n%s",         file, conditionMessage(e)))})
25: tools::buildVignettes(dir = ".", tangle = TRUE)
An irrecoverable exception occurred. R is aborting now ...
Segmentation fault (core dumped)
[ Finished: 2023-06-15 23:05:50 CEST ]