[ Started: 2024-10-07 16:36:57 CEST ] [ wppi v1.6.0 for BioC-3.20 from https://github.com/AnaGalhoz37/wppi@main (9b574a4 2022-11-02 08:18:02) ] * checking for file ‘./DESCRIPTION’ ... OK * preparing ‘wppi’: * checking DESCRIPTION meta-information ... OK * installing the package to build vignettes * creating vignettes ... ERROR --- re-building ‘wppi_workflow.Rmd’ using rmarkdown [2024-10-07 16:37:06] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:06] [INFO] [OmnipathR] Initialized cache: `/home/omnipath/.cache/OmnipathR`. [2024-10-07 16:37:06] [TRACE] [OmnipathR] Running on a build server, wiping cache. [2024-10-07 16:37:06] [TRACE] [OmnipathR] Cache is at `/home/omnipath/.cache/OmnipathR`. [2024-10-07 16:37:06] [TRACE] [OmnipathR] Contains 1 files. [2024-10-07 16:37:06] [TRACE] [OmnipathR] Cache is locked: FALSE. [2024-10-07 16:37:06] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:06] [SUCCESS] [OmnipathR] Removing all cache contents from `/home/omnipath/.cache/OmnipathR`. [2024-10-07 16:37:06] [TRACE] [OmnipathR] Pandoc version: `3.1.3`. [2024-10-07 16:37:06] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/local/R/4.4-3.20/OmnipathR/db/db_def.json` (encoding: UTF-8). [2024-10-07 16:37:06] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:07] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/local/R/4.4-3.20/OmnipathR/internal/magic_bytes.json` (encoding: UTF-8). [2024-10-07 16:37:07] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:07] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/local/R/4.4-3.20/OmnipathR/internal/urls.json` (encoding: UTF-8). [2024-10-07 16:37:07] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:07] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/local/R/4.4-3.20/OmnipathR/internal/id_types.json` (encoding: UTF-8). [2024-10-07 16:37:07] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:07] [TRACE] [OmnipathR] Cache locked: FALSE [2024-10-07 16:37:07] [INFO] [wppi] Executing WPPI workflow. [2024-10-07 16:37:07] [INFO] [wppi] Collecting database knowledge. [2024-10-07 16:37:07] [TRACE] [OmnipathR] Looking up in cache: `http://purl.obolibrary.org/obo/hp/hpoa/genes_to_phenotype.txt`. [2024-10-07 16:37:07] [INFO] [OmnipathR] Cache record does not exist: `http://purl.obolibrary.org/obo/hp/hpoa/genes_to_phenotype.txt` [2024-10-07 16:37:07] [TRACE] [OmnipathR] Could not find in cache, initiating download: `http://purl.obolibrary.org/obo/hp/hpoa/genes_to_phenotype.txt`. [2024-10-07 16:37:07] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:07] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:07] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:07] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:07] [INFO] [OmnipathR] Cache item `17e608c86c1284f1d80eb7aae56c9a652906c66e` version 1: status changed from `unknown` to `started`. [2024-10-07 16:37:07] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/17e608c86c1284f1d80eb7aae56c9a652906c66e-1.rds`. [2024-10-07 16:37:07] [INFO] [OmnipathR] Retrieving URL: `http://purl.obolibrary.org/obo/hp/hpoa/genes_to_phenotype.txt` [2024-10-07 16:37:07] [TRACE] [OmnipathR] Attempt 1/3: `http://purl.obolibrary.org/obo/hp/hpoa/genes_to_phenotype.txt` [2024-10-07 16:37:09] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/17e608c86c1284f1d80eb7aae56c9a652906c66e-1.rds`. [2024-10-07 16:37:09] [INFO] [OmnipathR] Download ready [key=17e608c86c1284f1d80eb7aae56c9a652906c66e, version=1] [2024-10-07 16:37:09] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:09] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:09] [INFO] [OmnipathR] Cache item `17e608c86c1284f1d80eb7aae56c9a652906c66e` version 1: status changed from `started` to `ready`. [2024-10-07 16:37:10] [SUCCESS] [OmnipathR] Human Phenotype Ontology (purl.obolibrary.org): downloaded 312812 records [2024-10-07 16:37:10] [TRACE] [OmnipathR] Looking up in cache: `http://current.geneontology.org/annotations/goa_human.gaf.gz`. [2024-10-07 16:37:10] [INFO] [OmnipathR] Cache record does not exist: `http://current.geneontology.org/annotations/goa_human.gaf.gz` [2024-10-07 16:37:10] [TRACE] [OmnipathR] Could not find in cache, initiating download: `http://current.geneontology.org/annotations/goa_human.gaf.gz`. [2024-10-07 16:37:10] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:10] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:10] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:10] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:10] [INFO] [OmnipathR] Cache item `4dccec1f0141d8846ba49e6f0eada25ebf0253fa` version 1: status changed from `unknown` to `started`. [2024-10-07 16:37:10] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/4dccec1f0141d8846ba49e6f0eada25ebf0253fa-1.rds`. [2024-10-07 16:37:10] [INFO] [OmnipathR] Retrieving URL: `http://current.geneontology.org/annotations/goa_human.gaf.gz` [2024-10-07 16:37:10] [TRACE] [OmnipathR] Attempt 1/3: `http://current.geneontology.org/annotations/goa_human.gaf.gz` [2024-10-07 16:37:16] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/4dccec1f0141d8846ba49e6f0eada25ebf0253fa-1.rds`. [2024-10-07 16:37:16] [INFO] [OmnipathR] Download ready [key=4dccec1f0141d8846ba49e6f0eada25ebf0253fa, version=1] [2024-10-07 16:37:16] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:16] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:16] [INFO] [OmnipathR] Cache item `4dccec1f0141d8846ba49e6f0eada25ebf0253fa` version 1: status changed from `started` to `ready`. [2024-10-07 16:37:17] [SUCCESS] [OmnipathR] Gene Ontology (current.geneontology.org): downloaded 773774 records [2024-10-07 16:37:17] [TRACE] [OmnipathR] Arguments for OmniPath query: [entity_types=protein,query_type=interactions] [2024-10-07 16:37:17] [INFO] [OmnipathR] Loading database `Ensembl and OMA organism names`. [2024-10-07 16:37:17] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:17] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:17] [INFO] [OmnipathR] Looking up in cache `https://www.ensembl.org/info/about/species.html`: key=7332486db7400730697234bad76ca0c8e4d00799, no version available. [2024-10-07 16:37:17] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:17] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:17] [INFO] [OmnipathR] Created new version for cache record 7332486db7400730697234bad76ca0c8e4d00799: version 1. [2024-10-07 16:37:17] [TRACE] [OmnipathR] Cache file path: /home/omnipath/.cache/OmnipathR/7332486db7400730697234bad76ca0c8e4d00799-1.html [2024-10-07 16:37:17] [INFO] [OmnipathR] Retrieving URL: `https://www.ensembl.org/info/about/species.html` [2024-10-07 16:37:17] [TRACE] [OmnipathR] Attempt 1/3: `https://www.ensembl.org/info/about/species.html` [2024-10-07 16:37:17] [TRACE] [OmnipathR] HTTP 200 [2024-10-07 16:37:17] [INFO] [OmnipathR] Download ready [key=7332486db7400730697234bad76ca0c8e4d00799, version=1] [2024-10-07 16:37:17] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:17] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:17] [INFO] [OmnipathR] Cache item `7332486db7400730697234bad76ca0c8e4d00799` version 1: status changed from `unknown` to `ready`. [2024-10-07 16:37:17] [TRACE] [OmnipathR] Looking up in cache: `https://omabrowser.org/All/oma-species.txt`. [2024-10-07 16:37:17] [INFO] [OmnipathR] Cache record does not exist: `https://omabrowser.org/All/oma-species.txt` [2024-10-07 16:37:17] [TRACE] [OmnipathR] Could not find in cache, initiating download: `https://omabrowser.org/All/oma-species.txt`. [2024-10-07 16:37:17] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:17] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:17] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:17] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:17] [INFO] [OmnipathR] Cache item `30e690cbb55dfc63b5903ab337f34ffc2f4be397` version 1: status changed from `unknown` to `started`. [2024-10-07 16:37:17] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`. [2024-10-07 16:37:17] [INFO] [OmnipathR] Retrieving URL: `https://omabrowser.org/All/oma-species.txt` [2024-10-07 16:37:17] [TRACE] [OmnipathR] Attempt 1/3: `https://omabrowser.org/All/oma-species.txt` [2024-10-07 16:37:17] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/30e690cbb55dfc63b5903ab337f34ffc2f4be397-1.rds`. [2024-10-07 16:37:17] [INFO] [OmnipathR] Download ready [key=30e690cbb55dfc63b5903ab337f34ffc2f4be397, version=1] [2024-10-07 16:37:17] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:17] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:17] [INFO] [OmnipathR] Cache item `30e690cbb55dfc63b5903ab337f34ffc2f4be397` version 1: status changed from `started` to `ready`. [2024-10-07 16:37:17] [INFO] [OmnipathR] Loaded database `Ensembl and OMA organism names`. [2024-10-07 16:37:17] [TRACE] [OmnipathR] Organism(s): 9606 [2024-10-07 16:37:17] [TRACE] [OmnipathR] Orthology targets: [2024-10-07 16:37:17] [TRACE] [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:17] [INFO] [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:17] [TRACE] [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:17] [INFO] [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:17] [TRACE] [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:17] [INFO] [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:17] [TRACE] [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:18] [INFO] [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath,pathwayextra,kinaseextra,ligrecextra&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:18] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:18] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:18] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:18] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:18] [INFO] [OmnipathR] Cache item `14b0e2906349bc073c3b72851e073e2886a90093` version 1: status changed from `unknown` to `started`. [2024-10-07 16:37:18] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/14b0e2906349bc073c3b72851e073e2886a90093-1.rds`. [2024-10-07 16:37:18] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/14b0e2906349bc073c3b72851e073e2886a90093-1.rds`. [2024-10-07 16:37:18] [INFO] [OmnipathR] Download ready [key=14b0e2906349bc073c3b72851e073e2886a90093, version=1] [2024-10-07 16:37:18] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:18] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:18] [INFO] [OmnipathR] Cache item `14b0e2906349bc073c3b72851e073e2886a90093` version 1: status changed from `started` to `ready`. [2024-10-07 16:37:20] [SUCCESS] [OmnipathR] Downloaded 80536 interactions. [2024-10-07 16:37:20] [INFO] [wppi] Finished collecting database knowledge. [2024-10-07 16:37:20] [INFO] [wppi] Using all HPO annotations available. [2024-10-07 16:37:21] [INFO] [wppi] Calculating weighted adjacency matrix. [2024-10-07 16:37:21] [INFO] [wppi] Preprocessing annotations (Gene Ontology). [2024-10-07 16:37:21] [INFO] [wppi] Preprocessing annotations (Human Phenotype Ontology). [2024-10-07 16:37:21] [INFO] [wppi] Graph size: 226 nodes and 2690 edges; GO: 3388 terms, 225 genes, 9926 annotations; HPO: 2738 terms, 116 genes, 8458 annotations. [2024-10-07 16:37:24] [INFO] [wppi] Finished calculating weighted adjacency matrix. [2024-10-07 16:37:24] [INFO] [wppi] Performing random walk with restart (restart probablilty: 0.4, threshold: 1e-05, number of genes: 226). [2024-10-07 16:37:27] [INFO] [wppi] Calculating WPPI gene scores (genes of interest: 8, genes in network: 226). [2024-10-07 16:37:27] [SUCCESS] [wppi] WPPI workflow completed. [2024-10-07 16:37:27] [TRACE] [OmnipathR] Arguments for OmniPath query: [datasets=omnipath,entity_types=protein,query_type=interactions] [2024-10-07 16:37:27] [TRACE] [OmnipathR] Organism(s): 9606 [2024-10-07 16:37:27] [TRACE] [OmnipathR] Orthology targets: [2024-10-07 16:37:27] [TRACE] [OmnipathR] Looking up in cache: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:27] [INFO] [OmnipathR] Cache record does not exist: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:27] [TRACE] [OmnipathR] Looking up in cache: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:27] [INFO] [OmnipathR] Cache record does not exist: `http://no-tls.omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:27] [TRACE] [OmnipathR] Attempting `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:27] [INFO] [OmnipathR] Retrieving URL: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:27] [TRACE] [OmnipathR] Attempt 1/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:27] [WARN] [OmnipathR] Failed to download `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` (attempt 1/3); error: HTTP error 500. [2024-10-07 16:37:32] [TRACE] [OmnipathR] Attempt 2/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:32] [WARN] [OmnipathR] Failed to download `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` (attempt 2/3); error: HTTP error 500. [2024-10-07 16:37:37] [TRACE] [OmnipathR] Attempt 3/3: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:41] [ERROR] [OmnipathR] Failed to download `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` (attempt 3/3); error: Recv failure: Connection reset by peer [2024-10-07 16:37:41] [WARN] [OmnipathR] Failed to download: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic`; error: Recv failure: Connection reset by peer [2024-10-07 16:37:41] [INFO] [OmnipathR] Successfully retrieved: `https://omnipathdb.org/interactions?genesymbols=yes&datasets=omnipath&organisms=9606&fields=sources,references,curation_effort&entity_types=protein&license=academic` [2024-10-07 16:37:41] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:41] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:41] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:41] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:41] [INFO] [OmnipathR] Cache item `4531fff8a97521fefd85568643520d934e90659c` version 1: status changed from `unknown` to `started`. [2024-10-07 16:37:41] [TRACE] [OmnipathR] Exporting object to RDS: `/home/omnipath/.cache/OmnipathR/4531fff8a97521fefd85568643520d934e90659c-1.rds`. [2024-10-07 16:37:41] [TRACE] [OmnipathR] Exported RDS to `/home/omnipath/.cache/OmnipathR/4531fff8a97521fefd85568643520d934e90659c-1.rds`. [2024-10-07 16:37:41] [INFO] [OmnipathR] Download ready [key=4531fff8a97521fefd85568643520d934e90659c, version=1] [2024-10-07 16:37:41] [TRACE] [OmnipathR] Reading JSON from `/home/omnipath/.cache/OmnipathR/cache.json` (encoding: UTF-8). [2024-10-07 16:37:41] [TRACE] [OmnipathR] JSON validation successful: TRUE [2024-10-07 16:37:41] [INFO] [OmnipathR] Cache item `4531fff8a97521fefd85568643520d934e90659c` version 1: status changed from `started` to `ready`. Quitting from lines 117-118 [database-knowledge-omnipath] (wppi_workflow.Rmd) Error: processing vignette 'wppi_workflow.Rmd' failed with diagnostics: no applicable method for 'mutate' applied to an object of class "list" --- failed re-building ‘wppi_workflow.Rmd’ SUMMARY: processing the following file failed: ‘wppi_workflow.Rmd’ Error: Vignette re-building failed. Execution halted [ Finished: 2024-10-07 16:37:41 CEST ]